Enantioselective Aza‐Henry Reactions Assisted by Zn^II and <i>N</i>‐Methylephedrine

Abstract

Hooray aza-Henry! A combination of zinc triflate, an amine base, and (−)-N-methylephedrine (NME), which can be easily recovered and reused, leads to high enantioselectivities in the aza-Henry reaction of N-Boc-protected aldimines and nitromethane (see scheme; Boc=tert-butyloxycarbonyl). Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2006/z502674_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.