Concepedia

Myocardin Regulates Vascular Response to Injury Through miR-24/-29a and Platelet-Derived Growth Factor Receptor-β

Amarnath Talasila, Haixiang Yu, Matthew Ackers‐Johnson, Martine Bot, Theo van Berkel, Martin R. Bennett, Ilze Bot, Sanjay Sinha

Arteriosclerosis Thrombosis and Vascular Biology · 2013 · 50 citations · 39 references

DOI

Abstract

Our results extend the function of myocardin from a developmental role to a pivotal regulator of SMC phenotype in response to injury, and this transcriptional coactivator may be an attractive target for novel therapeutic strategies in vascular disease.

References

39

Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis

Eva van Rooij, Lillian B. Sutherland, Jeffrey E. Thatcher et al. · Proceedings of the National Academy of Sciences · 2008 · 1.8K citations · Full text

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miR-145 and miR-143 regulate smooth muscle cell fate and plasticity

Kimberly R. Cordes, Neil T. Sheehy, Mark P. White et al. · Nature · 2009 · 1.6K citations · Full text

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A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure

Eva van Rooij, Lillian B. Sutherland, Ning Liu et al. · Proceedings of the National Academy of Sciences · 2006 · 1.5K citations · Full text

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Flk1-positive cells derived from embryonic stem cells serve as vascular progenitors

Jun K. Yamashita, Hiroshi Itoh, Masanori Hirashima et al. · Nature · 2000 · 1.4K citations

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MicroRNA Expression Signature and Antisense-Mediated Depletion Reveal an Essential Role of MicroRNA in Vascular Neointimal Lesion Formation

Ruirui Ji, Yunhui Cheng, Junming Yue et al. · Circulation Research · 2007 · 912 citations