Serum retinol‐binding protein 4 is not increased in obesity or obesity‐associated type 2 diabetes mellitus, but is reduced after relevant reductions in body fat following gastric bypass

Abstract

Serum RBP4 concentrations are not increased in obese patients with or without T2DM. A decrease in RBP4 levels was only observed after surgically induced weight loss accompanied by relevant reductions in body fat. RBP4 might be considered as a dynamic marker of negative energy balance being reduced during weight loss when a negative energy balance threshold is reached. Furthermore, RBP4 variation in the first month after RYGBP may be a predictor of weight loss success.