Annals of Internal Medicine · 2009 · 185 citations · 34 references
ICS therapy decreases inflammation and can attenuate decline in lung function in steroid-naive patients with moderate to severe COPD. Adding LABAs does not enhance these effects. .
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The Nature of Small-Airway Obstruction in Chronic Obstructive Pulmonary Disease
James C. Hogg, Fanny Chu, Soraya Utokaparch et al. · New England Journal of Medicine · 2004 · 3.7K citations · Full text