Concepedia

Tetramethylpyrazine inhibits production of nitric oxide and inducible nitric oxide synthase in lipopolysaccharide-induced N9 microglial cells through blockade of MAPK and PI3K/Akt signaling pathways, and suppression of intracellular reactive oxygen species

Hongtao Liu, Yuguang Du, Junlin He, Wenjuan Chen, Wenming Li, Yang Zhu, Yingxiong Wang, Chao Yu

Journal of Ethnopharmacology · 2010 · 60 citations · 44 references

Concepts

InflammationReactive Nitrogen SpecieNitric OxideMedicineImmunologyPharmacologyBrain-immune InteractionNeuroprotectionNeuroimmunologyNitrosative StressOxidative StressNeuroinflammation

References

44

Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase.

Q.W. Xie, Yumiko Kashiwabara, Carl Nathan · Journal of Biological Chemistry · 1994 · 2.2K citations · Full text

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB

Andrea Kauffmann-Zeh, Pablo Rodriguez‐Viciana, Eugen Ulrich et al. · Nature · 1997 · 1.2K citations

Signal Transduction, Signaling Pathway, Cell Regulation +9

The Nitric Oxide-Scavenging Properties of Ginkgo Biloba Extract EGb 761

Lucia Marcocci, J. J. Maguire, M T Droy-Lefaix et al. · Biochemical and Biophysical Research Communications · 1994 · 1K citations

Food Chemistry, Biochemistry, Medicine +5

Inflammatory Neurodegeneration Mediated by Nitric Oxide from Activated Glia-Inhibiting Neuronal Respiration, Causing Glutamate Release and Excitotoxicity

Anna Bal‐Price, Guy C. Brown · Journal of Neuroscience · 2001 · 681 citations · Full text

NADPH Oxidase Mediates Lipopolysaccharide-induced Neurotoxicity and Proinflammatory Gene Expression in Activated Microglia

Liya Qin, Yuxin Liu, Tongguang Wang et al. · Journal of Biological Chemistry · 2004 · 572 citations · Full text