Archives of General Psychiatry · 1990 · 511 citations · 31 references
Life SciencesImmunologyPsychiatryCancer ImmunologyPsychoneuroimmunologyTumor ImmunologyCell-mediated ImmunityCoping StrategiesCytotoxic T Lymphocyte ResponsesImmune ResponseNatural Killer Cell BiologyTumor-infiltrating LymphocytesAffective State AssessmentCancer-related Psychological DistressCd4+ T Helper Cell ResponsesImmune Function IndicatorsInnate Immune FunctionPsychoneuroimmune MechanismsShort-term Group TherapyStress-induced Immune Changes
Most malignant melanoma patients experience high psychological distress despite a generally good prognosis. The study evaluated the immediate and long‑term effects of a 6‑week structured psychiatric group intervention on distress and coping in postsurgical melanoma patients. The intervention combined health education, problem‑solving skill enhancement, stress‑management techniques, and psychological support. Participants showed increased vigor and active coping immediately after the intervention, with significantly lower depression, fatigue, confusion, and mood disturbance at 6‑month follow‑up compared to controls.
• We evaluated the immediate and long-term effects on psychological distress and coping methods of a 6-week, structured, psychiatric group intervention for postsurgical patients with malignant melanoma. The intervention consisted of health education, enhancement of problem-solving skills, stress management (eg, relaxation techniques), and psychological support. In spite of good prognosis, most patients had high levels of psychological distress at baseline, comparable with other patients with cancer. However, at the end of brief psychiatric intervention, the experimental subjects (n = 38), while not without some distress, exhibited higher vigor and greater use of active-behavioral coping than the controls (n = 28). At 6 months' follow-up, the group differences were even more pronounced. The intervention-group patients then showed significantly lower depression, fatigue, confusion, and total mood disturbance as well as higher vigor. They were also using significantly more active-behavioral and active-cognitive coping than the controls. These results indicate that a short-term psychiatric group intervention for patients with malignant melanoma effectively reduces psychological distress and enhances longer-term effective coping.
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Group Support for Patients With Metastatic Cancer
David Spiegel · Archives of General Psychiatry · 1981 · 868 citations
Psychosocial Modifiers of Immunocompetence in Medical Students
Janice K. Kiecolt‐Glaser, W.L. Garner, Carl E. Speicher et al. · Psychosomatic Medicine · 1984 · 791 citations
Nursing, Immunology, Psychology +17
Marital quality, marital disruption, and immune function.
Janice K. Kiecolt‐Glaser, Lloyd D. Fisher, Paula Ogrocki et al. · Psychosomatic Medicine · 1987 · 668 citations
Nursing, Immunology, Psychiatry +16