Visible‐Light‐Induced Trifluoromethylation of <i>N</i>‐Aryl Acrylamides: A Convenient and Effective Method To Synthesize CF₃‐Containing Oxindoles Bearing a Quaternary Carbon Center

Abstract

Trifluoromethylation/arylation: N-aryl acrylamides undergo visible-light-induced tandem trifluoromethylation/arylation in the presence of a ruthenium photocatalyst with Togni's reagent as the CF3 source. This reaction serves as a powerful and ecofriendly synthetic method for the preparation of a variety of CF3 -containing oxindoles bearing a quaternary carbon center.