Concepedia

Disposition of the monoclonal antibody-vinca alkaloid conjugate KS1/4-DAVLB (LY256787) and free 4-desacetylvinblastine in tumor-bearing nude mice.

M E Spearman, R M Goodwin, L D Apelgren, Thomas F. Bumol

Journal of Pharmacology and Experimental Therapeutics · 1987 · 24 citations · 0 references

Concepts

PharmacyOncologyPharmacologyCancer PharmacologyMolecular OncologyPharmacokinetics Of Anticancer AgentsAntibody-drug Conjugate PharmacokineticsDrug DispositionOncology PharmacologyPharmacokinetics Of Anticancer DrugsPharmacokinetics Of Monoclonal AntibodiesLung AdenocarcinomaPlasma PharmacokineticsRadiopharmaceutical PharmacokineticsTumor Tissue TargetingTumor Uptake KineticsTumor Uptake MechanismsTumor Volume Of DistributionVinca Alkaloid Pharmacokinetics