Use of ¹⁸F-FDG PET to Predict Response to First-Line Tuberculostatics in HIV-Associated Tuberculosis

Abstract

In this pilot study, a cutoff of 5 or more involved lymph node bastions allowed for separation of tuberculostatic responsive and nonresponsive tuberculosis-infected HIV patients with a sensitivity of 88%, a specificity of 81%, and a negative predictive value of 93%. These findings warrant confirmation by additional studies on larger cohorts of patients.