SYNERGISTIC ACTION OF STEROIDS AND SPERMATOCELE FLUID ON IN VITRO PROLIFERATION OF PROSTATE STROMA

Abstract

These in vitro observations indicate that testis epididymal secretions contain androgen/STEP synergistic and androgen independent STEP factors promoting prostate stromal growth. These factors are not heparin binding. These observations are consistent with the concept that, in addition to the production of steroids, the testis produces non-androgenic factors that act in concert with, as well as independently of, androgen to stimulate prostatic growth.