Failure of Mebendazole in the Treatment of Humans with Trichinella spiralis Infection at the Stage of Encapsulating Larvae

Abstract

Trichinella spiralis larvae infective for laboratory mice were collected from muscle biopsies performed at different times (from 1 day to 16 months) following the end of treatment, indicating the failure of mebendazole to kill Trichinella parasites when they are encapsulating in muscles.