Role of Preexisting Disability in Patients Treated With Intravenous Thrombolysis for Ischemic Stroke

Abstract

Prestroke disability does not seem to independently increase the risk of symptomatic intracranial hemorrhage after thrombolysis. Despite higher mortality, 1 in 3 previously disabled patients may return to his/her prestroke mRS. Therefore, they should not be routinely excluded from thrombolytic therapy.