Chromosome 1p21.3 microdeletions comprising <i>DPYD</i> and <i>MIR137</i> are associated with intellectual disability

Abstract

This study showed that dosage effects of MIR137 are associated with 1p21.3 microdeletions and may therefore contribute to the ID phenotype in patients with deletions harbouring this miRNA. A local effect at the synapse might be responsible.