Publication | Closed Access
A General and Practical Method of Alkynyl Indole and Benzofuran Synthesis via Tandem Cu- and Pd-Catalyzed Cross-Couplings
163
Citations
6
References
2007
Year
2-Alkynyl IndolesEngineeringOrganic ChemistryChemistryChemical EngineeringAlkynyl IndoleNew TandemCross-coupling ReactionDiversity-oriented SynthesisCatalysisBenzofuran SynthesisSynthesis MethodAsymmetric CatalysisEnantioselective SynthesisTandem Cu-Biomolecular EngineeringNatural SciencesAccessible Gem-dibromovinyl SubstratesSynthetic Chemistry
A new tandem coupling approach to synthesize 2-alkynyl indoles and benzofurans is described. This reaction utilizes easily accessible gem-dibromovinyl substrates and terminal alkynes and proceeds via Pd/C- and CuI-catalyzed tandem Ullman/Sonogashira couplings.
| Year | Citations | |
|---|---|---|
Page 1
Page 1