Gut · 1977 · 80 citations · 12 references
MedicinePharmacologyPharmacotherapyInflammationEndocrine DiseasePancreatic DiseasesPancreatic DisordersPancreatic EndocrinologyPancreatic HormonesPancreatic PathologyAmylase ProductionExocrine Pancreatic DiseaseExocrine Pancreatic DysfunctionPancreatic Exocrine FunctionPancreatic Hormone SecretionPancreatic Secretory ResponseSomatostatin PharmacologySomatostatin Physiology
Because somatostatin (SRIF) reduces exocrine pancreatic secretion, its effect on acute pancreatitis was investigated in rats. Linear SRIF reduced serum amylase and lipase but had no effect on pancreatic necrosis, oedema, leucocyte infiltration, and enzyme content. The mortality rate was not reduced. These results do not recommend the use of SRIF in the treatment of acute pancreatitis.
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Somatostatin Suppresses Secretin and Pancreatic Exocrine Secretion
Guenther Boden, Michael C. Sivitz, Oliver E. Owen et al. · Science · 1975 · 268 citations
Determination ok amylase activity in biological fluids
Harold V. Street, John K. Close · Clinica Chimica Acta · 1956 · 175 citations
Influence of Glucagon on Pancreatic Exocrine Secretion in Man
Walter P. Dyck, E. Clinton Texter, John Lasater et al. · Gastroenterology · 1970 · 143 citations