Radiotherapy of liposarcomas

Abstract

A review of the literature of time-dose relationships of liposarcoma is given. The radiotherapeutic data on 15 measurable liposarcoma sites, together with 45 sites collected from the literature, are subjected to a Strandqvist plot analysis using the modified Ellis' formula TSD = D.T-alpha. The recovery coefficient alpha is thought to be rather high, of the order alpha = 0.5. This suggests that the use of a few large fractions in therapy may be beneficial.