Antimicrobial Agents and Chemotherapy · 2007 · 16 citations · 15 references
DentistryMicrobiologyOral BiologyBacteriologyMedical MicrobiologyOral MicrobiologyAntimicrobial PeptidesBiofilm-associated ResistanceOral Bacterial InfectionsOral Microbial PathogenesisOral Microbial VirulencePeriodontal MicrobiologyAntibacterial PeptidesAntimicrobial Peptide ActivityFusobacterium SpeciesOral Biofilm InhibitionOral Pathogenic MicroorganismsOral PorphyromonasPorphyromonas SpeciesStreptococcus Species
The efficacy of a novel synthetic antimicrobial peptide (WLBU2) was evaluated against three oral microorganisms (grown planktonically): Streptococcus gordonii, Fusobacterium nucleatum, and Porphyromonas gingivalis. WLBU2 killed all three species, with F. nucleatum being the most susceptible. WLBU2 also reduced the bacterial burden of S. gordonii and F. nucleatum biofilms.
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Defining the Normal Bacterial Flora of the Oral Cavity
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