Linkage of cytokine genes to rheumatoid arthritis. Evidence of genetic heterogeneity

Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM).

Richard S. Spielman, Ralph McGinnis, Warren J. Ewens · PubMed · 1993 · 3.7K citations

Life Sciences, Genetics, Molecular Genetics +15

Linkage strategies for genetically complex traits. II. The power of affected relative pairs.

Neil Risch · PubMed · 1990 · 871 citations

Life Sciences, Biostatistics, Genetics +16

TWIN CONCORDANCE RATES FOR RHEUMATOID ARTHRITIS: RESULTS FROM A NATIONWIDE STUDY

Alan J. Silman, Alex J. MacGregor, Wendy Thomson et al. · Lara D. Veeken · 1993 · 614 citations

Life Sciences, Clinical Sciences, Genetics +15

Assessing the role of HLA-linked and unlinked determinants of disease.

Neil Risch · PubMed · 1987 · 543 citations

Life Sciences, Immunology, Autoimmunity +11

Generalized autoimmune disease in interleukin‐2‐deficient mice is triggered by an uncontrolled activation and proliferation of CD4⁺ T cells

Benjamin Sadlack, Jürgen Löhler, Hubert Schorle et al. · European Journal of Immunology · 1995 · 423 citations

Life Sciences, Immunology, Pathology +17