Morphine stimulates cancer progression and mast cell activation and impairs survival in transgenic mice with breast cancer

Randomized Clinical Trial of an Implantable Drug Delivery System Compared With Comprehensive Medical Management for Refractory Cancer Pain: Impact on Pain, Drug-Related Toxicity, and Survival

Thomas J. Smith, Peter S. Staats, Timothy R. Deer et al. · Journal of Clinical Oncology · 2002 · 718 citations

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Morphine stimulates angiogenesis by activating proangiogenic and survival-promoting signaling and promotes breast tumor growth.

Kalpna Gupta, Smita Kshirsagar, Liming Chang et al. · PubMed · 2002 · 532 citations

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Prostate and mammary adenocarcinoma in transgenic mice carrying a rat C3(1) simian virus 40 large tumor antigen fusion gene.

Miriam R. Anver, Lisa Garrett, J E Green · Proceedings of the National Academy of Sciences · 1994 · 357 citations

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Proteinase-activated receptor 2 sensitizes transient receptor potential vanilloid 1, transient receptor potential vanilloid 4, and transient receptor potential ankyrin 1 in paclitaxel-induced neuropathic pain

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Medicine, Neurobiology, Pharmacology +15

The Novel Role of the Mu Opioid Receptor in Lung Cancer Progression

Biji Mathew, Frances E. Lennon, Jessica Siegler et al. · Anesthesia & Analgesia · 2010 · 260 citations

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