Synthesis of α-indanones via intramolecular direct arylation with cyclopropanol-derived homoenolates

Abstract

A palladium-catalysed, tandem cyclopropanol rearrangement and direct arylation approach for the synthesis of 1-indanones is reported. The reaction is generally high yielding, uses oxygen as the terminal oxidant and tolerates a range of functional groups on the aryl ring.