Detection of the HE4 protein in urine as a biomarker for ovarian neoplasms

Internal validation of predictive models

Ewout W. Steyerberg, Frank E. Harrell, Gerard Borsboom et al. · Journal of Clinical Epidemiology · 2001 · 2.6K citations

Computing, Computer Science, Machine Learning +13

A novel multiple marker bioassay utilizing HE4 and CA125 for the prediction of ovarian cancer in patients with a pelvic mass

Richard G. Moore, D. Scott McMeekin, Amy Brown et al. · Gynecologic Oncology · 2008 · 866 citations

Medicine, Gynecology, Oncology +15

Ovarian Carcinoma Subtypes Are Different Diseases: Implications for Biomarker Studies

Martin Köbel, Steve E. Kalloger, Niki Boyd et al. · PLoS Medicine · 2008 · 820 citations · Full text

Medicine, Oncology, Pathology +17

Molecular cloning of mesothelin, a differentiation antigen present on mesothelium, mesotheliomas, and ovarian cancers.

King‐Jen Chang, Ira Pastan · Proceedings of the National Academy of Sciences · 1996 · 742 citations

Life Sciences, Molecular Biology, Oncology +17

The HE4 (WFDC2) protein is a biomarker for ovarian carcinoma.

Ingegerd Hellström, John Raycraft, Martha Hayden-Ledbetter et al. · PubMed · 2003 · 719 citations

Life Sciences, Molecular Biology, Oncology +17