A [¹⁴C]iodoantipyrine Study of Inter-Regional Correlations of Neural Substrates Following Central Post-Stroke Pain in Rats

Abstract

These results corroborate previous findings that the STT and thalamocingulate pathway are involved in the pathophysiological mechanisms of CPSP symptoms. The mPFC, amygdala, and periaqueductal gray emerged as having important correlations in pain processing in CPSP. The present data provide a basis for a neural correlation hypothesis of CPSP, with implications for CPSP treatment.