Gd‐Encapsulated Carbonaceous Dots with Efficient Renal Clearance for Magnetic Resonance Imaging

Hongmin Chen, Geoffrey D. Wang, Wei Tang, Trever Todd, Zipeng Zhen, Chu F. Tsang, Khan Hekmatyar, Taku Cowger, Richard Hubbard, Weizhong Zhang,

Advanced Materials · 2014 · 183 citations · 23 references

Concepts

Abstract

Nanoprobes for MRI and optical imaging are demonstrated. Gd@C-dots possess strong fluorescence and can effectively enhance signals on T1 -weighted MR images. The nanoprobes have low toxicity, and, despite a relatively large size, can be efficiently excreted by renal clearance from the host after systemic injection.

References

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