Metabolic Biofouling of Glucose Sensors <i>in Vivo</i>: Role of Tissue Microhemorrhages

Abstract

These results support our hypothesis that tissue hemorrhage and resulting blood clots near the sensor can result in lowered local blood glucose concentrations due to metabolism of glucose by the clot. The lowered local blood glucose concentration led to low glucose readings from the still functioning sensor that did not reflect the systemic glucose level.