Heterogeneous Catalytic Sulfimidation using Immobilized Cu(acac)₂

Abstract

Abstract The heterogeneous sulfimidation of various sulfides by microencapsulated copper(II) acetylacetonate, [MC‐Cu(acac) 2 ], and Cu(acac) 2 immobilized in ionic liquids using [ N ‐( p ‐tolylsulfonyl)imino]phenyliodinane (PhINTs) as nitrene donor has been developed to afford the corresponding sulfimides in good to excellent yields. In the presence of a chiral bis(oxazoline) as ligand, asymmetric induction occurs to afford the chiral sulfimides (up to 50% ee). The ionic liquid containing the immobilized bis(oxazoline)‐copper catalyst can be reused for several cycles with consistent activity and enantioselectivity.