Concepedia

Comparing the reduction of nitroimidazoles in bacteria and mammalian tissues and relating it to biological activity

Peter Goldman, Ronald L. Koch, Tin-Chuen Yeung, Ewan J. T. Chrystal, Bernard B. Beaulieu, Martha A. McLafferty, Gillian Sudlow

Biochemical Pharmacology · 1986 · 66 citations · 34 references

DOI

Concepts

References

34

Electron-Affinic SensitizationVII. A Correlation between Structures, One-Electron Reduction Potentials, and Efficiencies of Nitroimidazoles as Hypoxic Cell Radiosensitizers

G.E. Adams, I. R. Flockhart, C. E. Smithen et al. · Radiation Research · 2012 · 349 citations

, , +15

Oxygen-sensitive and -insensitive nitroreduction by Escherichia coli and rat hepatic microsomes.

Francis J. Peterson, Ronald P. Mason, J Hovsepian et al. · Journal of Biological Chemistry · 1979 · 304 citations · Full text

, , +13

Electron-Affinic Sensitization: VII. A Correlation between Structures, One-Electron Reduction Potentials, and Efficiencies of Nitroimidazoles as Hypoxic Cell Radiosensitizers

G.E. Adams, I. R. Flockhart, C. E. Smithen et al. · Radiation Research · 1976 · 297 citations

, , +14

Antitrichomonad Action, Mutagenicity, and Reduction of Metronidazole and Other Nitroimidazoles

Donald G. Lindmark, Miklós Müller · Antimicrobial Agents and Chemotherapy · 1976 · 240 citations · Full text

, , +9

Mutagenicity of metronidazole: Activation by mammalian liver microsomes

Herbert S. Rosenkranz, William T. Speck · Biochemical and Biophysical Research Communications · 1975 · 235 citations

, , +9