Concepedia

Singlet‐Oxygen‐Sensitizing Near‐Infrared‐Fluorescent Multimodal Nanoparticles

Edakkattuparambil Sidharth Shibu, Sakiko Sugino, Kenji Ono, Hironobu Saito, Ayama Nishioka, Shohei Yamamura, Makoto Sawada, Yoshio Nosaka, Vasudevanpillai Biju

Angewandte Chemie International Edition · 2013 · 61 citations · 35 references

DOI

Concepts

Abstract

Nanoprobes based on quantum clusters (QC) with near-infrared fluorescence, magnetic-resonance-imaging contrast, and singlet-oxygen-sensitized intracellular fluorescence are studied. The generation of singlet oxygen and singlet-oxygen-sensitized fluorescence uncaging by magnetic and NIR-emitting nanoparticles are exploited for multimodal bioimaging in vitro.

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