Interaction of Myxoviruses with Human Blood Platelets in vitro.

Abstract

1. Influenza and Newcastle Disease Viruses are adsorbed to red blood cells and to platelets in a similar manner. Evidence is presented indicating that there exists similar virus receptors on the surface of the red blood cells and of the platelets. 2. Virus is adsorbed to platelets in the absence of cations as well as after its previous elution and after RDE treatment of platelets. Furthermore elution of the virus from platelets is much slower and less complete than that from red blood cells. These phenomena may be due to incorporation of virus particles into the platelets.