Concepedia

Publication | Open Access

Prospective Phase II Study of FOLFIRI for mCRC in Japan, Including the Analysis of UGT1A1*28/*6 Polymorphisms

DOIFull Paper Access

54

Citations

20

References

2011

Year

Yusuke Okuyama, Shoichi Hazama, Hiroshi Nozawa, Mariko Kobayashi, Kenichi Takahashi, Koshi Fujikawa, Takaharu Kato, N. Nagata, Hideo Kimura, Koji Oba,
Japanese Journal of Clinical Oncology

Abstract

FOLFIRI is effective and tolerable for Japanese metastatic colorectal cancer patients. Homozygosity for UGT1A1 28 or 6 and heterozygosity for both UGT1A1 28 and 6 are associated with severe neutropenia.

References

YearCitations

Page 1