USE OF VON WILLEBRAND DISEASED KIDNEY AS DONOR IN A PIG-TO-PRIMATE MODEL OF XENOTRANSPLANTATION1

Abstract

The use of vWD organs did not improve the survival time of grafted kidneys in this xenotransplantation model. Further studies on the use of vWD organs, in association with other therapeutic approaches, such as complement inhibition, are nevertheless necessary to evaluate the usefulness of vWF deficiency as an adjunctive therapy to decrease the coagulation process during xenograft rejection.