Endothelial Nitric Oxide Synthase genotypes in the etiology of retinopathy of prematurity in premature infants

Abstract

The present data suggest ethnic stratification of genotypes. Mutant -786C and 894T alleles are significant risk factors in the development of ROP, and suggest a strong association between eNOS polymorphisms and the disease. It is interesting to know if a larger dataset of ROP patients can confirm our initial findings.