Na+/K+-ATPase 2-subunit (AMOG) expression abrogates invasion of glioblastoma-derived brain tumor-initiating cells

Abstract

AMOG expression inhibits GBM invasion. Its downregulation increases invasion in glial cells and may also represent an important step in BTIC differentiation. These data provide compelling evidence implicating the role of AMOG in glioma invasion and provide impetus for further investigation.