COMPUTERIZED HISTOMORPHOMETRIC ASSESSMENT OF PROTOCOL RENAL TRANSPLANT BIOPSY SPECIMENS FOR SURROGATE MARKERS OF CHRONIC REJECTION

Abstract

Grafts with poorer long-term function can be predicted using 6-month protocol biopsy specimens immunostained for collagen III. This should prove to be a useful ad interim surrogate marker of allograft damage in studies addressing the effects of new immunosuppressive agents on the development of chronic rejection.