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Scintigraphic Detection of Pulmonary Bacterial Infections with Labeled Thyroid Hormones and Pertechnetate
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1971
Year
EngineeringKlebsiella PneumoniaePathologyUtilizing 99MtcRespiratory InfectionSepsisInfection ControlLaboratory MedicineActive InfectionNuclear MedicineAntimicrobial ResistancePulmonary Bacterial InfectionsScintigraphic DetectionTuberculosisLabeled Thyroid HormonesClinical MicrobiologyIsotopic LocalizationAntibioticsThyroid DiseaseMicrobiologyMedicineDiagnostic Microbiology
In 14 of 16 patients, scintigraphic detection of acute pulmonary bacterial infections was observed utilizing 99mTc pertechnetate, 131I-thyroxine, and 13II-triiodothyronine. Failure to find some isotopic localization in patients with antibiotically treated pulmonary bacterial or tuberculous infections and pulmonary carcinoma indicates that an active infection is a prerequisite for this condition. These isotopes appear to concentrate in leukocytes which are actively phagocytizing bacteria.