Publication | Closed Access
Synthesis of 1,3-dioxo-hexahydropyrido[1,2-c][1,3]diazepine carboxylates, a new bicyclic skeleton formed by ring expansion–RCM methodology
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Citations
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References
2005
Year
Medicinal ChemistryBioorganic ChemistryNew Bicyclic SkeletonEngineeringHeterocyclicNatural SciencesNew 1,3-Diazepan-2,4-dioneExpansion–rcm MethodologyOrganic ChemistryElegant Synthetic PathwayCatalysisSynthetic ChemistryChemistryHeterocycle ChemistryPharmacologyPyroglutamate EstersBiomolecular Engineering
A short and elegant synthetic pathway was developed for the synthesis of 1,3-dioxo-hexahydropyrido[1,2-c][1,3]diazepine carboxylates, a new 1,3-diazepan-2,4-dione containing bicyclic moiety, starting from pyroglutamate esters.
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