Preclinical evaluation of [ ¹¹¹ In]-DOTA-trastuzumab for clinical trials

Abstract

In vitro and in vivo/SPECT imaging in SkBr3-bearing mice demonstrated that ¹¹¹ In-DOTA-trastuzumab is a potential compound for molecular imaging of SPECT for diagnosis and follow-up of HER2 expression in oncology.