Concepedia

Depression and Survival in Metastatic Non–Small-Cell Lung Cancer: Effects of Early Palliative Care

William F. Pirl, Joseph A. Greer, Lara Traeger, Vicki A. Jackson, Inga T. Lennes, Emily R. Gallagher, Pedro Emilio Perez‐Cruz, Rebecca S. Heist, Jennifer S. Temel

Journal of Clinical Oncology · 2012 · 224 citations · 22 references

DOIFull text

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Abstract

Depression predicted worse survival in patients with newly diagnosed metastatic NSCLC. Although EPC was associated with greater improvement in depression at 12 weeks, the data do not support the hypothesis that treatment of depression mediated the observed survival benefit from EPC.

References

22

The moderator-mediator variable distinction in social psychological research: Conceptual, strategic, and statistical considerations.

Reuben M. Baron, David A. Kenny · Journal of Personality and Social Psychology · 1986 · 71.8K citations

, , +14

The moderator–mediator variable distinction in social psychological research: Conceptual, strategic, and statistical considerations.

Reuben M. Baron, David A. Kenny · Journal of Personality and Social Psychology · 1986 · 69.4K citations

, , +8

Validation and Utility of a Self-report Version of PRIME-MD<SUBTITLE>The PHQ Primary Care Study</SUBTITLE>

Robert L. Spitzer · JAMA · 1999 · 9.6K citations

Early Palliative Care for Patients with Metastatic Non–Small-Cell Lung Cancer

Jennifer S. Temel, Joseph A. Greer, Alona Muzikansky et al. · New England Journal of Medicine · 2010 · 7.2K citations

Decrease in Depression Symptoms Is Associated With Longer Survival in Patients With Metastatic Breast Cancer: A Secondary Analysis

Janine Giese‐Davis, Kate Collie, Kate M. Rancourt et al. · Journal of Clinical Oncology · 2010 · 461 citations · Full text