Concepedia

A new approach to synthesis of 3,3‐dialkyl‐3,4‐dihydroisoquinoline derivatives

Yu. V. Shklyaev, M. A. Yeltsov, Yu. S. Rozhkova, Valery M. Dembitsky

Heteroatom Chemistry · 2004 · 25 citations · 6 references

DOI

Concepts

Abstract

Abstract The synthesis of 3,3‐dialkyl‐3,4‐dihydroisoquinolines via heterocyclization in three‐component reaction of an activated arene with isobutyraldehyde and nitriles is described. © 2004 Wiley Periodicals, Inc. Heteroatom Chem 15:486–493, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20049

References

6

An improved degradation procedure for determination of the absolute configuration in chiral isoquinoline and β-carboline derivatives

Gerhard Bringmann, Ralf God, Manuela Schäffer · Phytochemistry · 1996 · 73 citations

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Enantioselective Synthesis ofProtoberberine Alkaloids via (-)-Sparteine-mediatedAsymmetric Condensation-Cyclisation of <i>o</i>-ToluamideAnions with 3,4-Dihydroisoquinolines

Ligong Liu · Synthesis · 2003 · 27 citations

, , +9

Asymmetric synthesis of (R)-(+)- and (S)-(−)-2,3-methylenedioxy-8-oxoberbine (gusanlung D)

Maria Chrzanowska, Agnieszka Dreas, Maria D. Rozwadowska · Tetrahedron Asymmetry · 2004 · 25 citations

, , +2

Oxiranes in the Ritter reaction: synthesis of 6,7-(or 5,8-)dimethoxy-3,4-dihydroisoquinolines by a tandem alkylation–cyclization procedure

Yurii V. Shklyaev · Mendeleev Communications · 1998 · 16 citations

Alternative Synthesis of Septic Shock Candidate 3,4-Dihydro-3,3-dimethylisoquinoline <i>N</i>-Oxide (MDL 101002) Utilizing an Improved Pictet−Spengler Reaction

Timothy Watson · The Journal of Organic Chemistry · 1998 · 13 citations

, , +11