Doxorubicin induces cardiomyocyte dysfunction via a p38 MAP kinase-dependent oxidative stress mechanism

Doxorubicin cardiotoxicity: analysis of prevailing hypotheses

Richard D. Olson, Phillip S. Mushlin · The FASEB Journal · 1990 · 685 citations

The protective role of manganese superoxide dismutase against adriamycin-induced acute cardiac toxicity in transgenic mice.

Hsiu‐Chuan Yen, Terry D. Oberley, S Vichitbandha et al. · Journal of Clinical Investigation · 1996 · 459 citations · Full text

Lipid Peroxidation, Cell Death, Manganese Superoxide Dismutase +17

Doxorubicin-induced apoptosis: Implications in cardiotoxicity

Balaraman Kalyanaraman, Joy Joseph, Shashi Kalivendi et al. · Molecular and Cellular Biochemistry · 2002 · 286 citations

Hsp10 and Hsp60 modulate Bcl-2 family and mitochondria apoptosis signaling induced by doxorubicin in cardiac muscle cells

Yuexin Shan · Journal of Molecular and Cellular Cardiology · 2003 · 233 citations

Inflammation, Signal Transduction, Mitochondria Apoptosis +11

AT ₁ Blockade Prevents Glucose-Induced Cardiac Dysfunction in Ventricular Myocytes

Jamie R. Privratsky, Loren E. Wold, James R. Sowers et al. · Hypertension · 2003 · 222 citations · Full text

Cardiac Muscle, Hypertension, Heart Failure +18