An Arthritis‐Suppressive and Treg Cell–Inducing CD4+ T Cell Epitope Is Functional in the Context of HLA‐Restricted T Cell Responses

Abstract

These results demonstrated a conserved fine specificity and functionality of B29-induced Treg cell responses in the context of the human MHC. Based on these findings, a path for translation of the experimental findings for B29 into a clinical immunomodulatory therapeutic approach is within reach.