Clinical and Applied Thrombosis/Hemostasis · 2006 · 19 citations · 4 references
MedicineObstetricsSurgeryObstetric AnesthesiaObstetric HemorrhageTransfusion MedicineBlood Transfusion ManagementCesarean DeliveryCesarean SectionHemorrhagic ShockIntrapartum HemorrhageObstetric Hemorrhage ManagementBleedingCesarean Section Hemorrhage ControlEmergency Cesarean SectionFresh Frozen Plasma TherapyHemorrhagic Shock PharmacotherapyIntravenous Bolus InjectionRecombinant Activated Factor ViiUterotonic Surgical Management
Hemorrhagic shock developed in a 29-year-old nullipara without coagulopathy after emergency caesarean section. Treatment with uterotonic drugs, prostaglandins, and conservative procedures with transfusion of packed red cells and fresh-frozen plasma failed to control the diffuse vaginal and uterine bleeding. Finally an intravenous bolus injection of 90 microg/kg recombinant activated factor VII (rFVIIa, NovoSeven, Novo Nordisk A/S, Bagsvaerd, Denmark), was given and showed success within 20 minutes after administration, without any side effects.
4