Impact of pathogen burden in patients with coronary artery disease in relation to systemic inflammation and variation in genes encoding cytokines

C-Reactive Protein and Other Markers of Inflammation in the Prediction of Cardiovascular Disease in Women

Paul M. Ridker, Charles H. Hennekens, Julie E. Buring et al. · New England Journal of Medicine · 2000 · 5.9K citations · Full text

Medicine, Cardiology, Clinical Sciences +15

The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis.

Daniel Fishman, Gary Faulds, Rachel Jeffery et al. · Journal of Clinical Investigation · 1998 · 2.2K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Interleukin-6 Gene −174G>C and −572G>C Promoter Polymorphisms Are Strong Predictors of Plasma Interleukin-6 Levels After Coronary Artery Bypass Surgery

David Brull, Hugh Montgomery, Julie Sanders et al. · Arteriosclerosis Thrombosis and Vascular Biology · 2001 · 409 citations · Full text

Life Sciences, Genetics, Immunology +17

The interleukin-6 −174 G/C promoter polymorphism is associated with risk of coronary heart disease and systolic blood pressure in healthy men

Steve E. Humphries · European Heart Journal · 2001 · 395 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Interleukin-6 ( <i>IL-6</i> ) and the Prognosis of Abdominal Aortic Aneurysms

Keith G. Jones, David Brull, Louise Brown et al. · Circulation · 2001 · 363 citations · Full text

Veterinary Medicine, Immunology, Clinical Immunology +15