Smoking increases peptidylarginine deiminase 2 enzyme expression in human lungs and increases citrullination in BAL cells

A new model for an etiology of rheumatoid arthritis: Smoking may trigger HLA–DR (shared epitope)–restricted immune reactions to autoantigens modified by citrullination

Lars Klareskog, Patrik Stolt, Karin Lundberg et al. · Arthritis & Rheumatism · 2005 · 1.5K citations

Life Sciences, Immunology, Pathobiology +17

Expression and activity of citrullinating peptidylarginine deiminase enzymes in monocytes and macrophages

E.R. Vossenaar · Annals of the Rheumatic Diseases · 2004 · 452 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

Citrullination is an inflammation-dependent process

Dimitrios Makrygiannakis, Erik af Klint, Ingrid E. Lundberg et al. · Annals of the Rheumatic Diseases · 2006 · 296 citations · Full text

Medicine, Immunology, Pathology +16

Acute cigarette smoke exposure induces apoptosis of alveolar macrophages

Kazutetsu Aoshiba, Jun Tamaoki, Atsushi Nagai · American Journal of Physiology-Lung Cellular and Molecular Physiology · 2001 · 218 citations

Pharmacy, Cell Biology, Toxicology +16

Selective Deimination of Vimentin in Calcium Ionophore-Induced Apoptosis of Mouse Peritoneal Macrophages

Hiroaki Asaga, Michiyuki Yamada, Tatsuo Senshu · Biochemical and Biophysical Research Communications · 1998 · 208 citations

Life Sciences, Biochemistry, Cell Biology +15