Mixing in industrial Rushton turbine-agitated reactors under aerated conditions

Substrate gradient formation in the large-scale bioreactor lowers cell yield and increases by-product formation

F. Bylund, Éric Collet, Sven‐Olof Enfors et al. · Bioprocess Engineering · 1998 · 228 citations

Life Sciences, Bioengineering, Biotechnology +16

Substrate gradients in bioreactors: origin and consequences

Gen Larsson, M. T�rnkvist, Erik Wernersson et al. · Bioprocess and Biosystems Engineering · 1996 · 201 citations

Engineering, Bioengineering, Biotechnology +12

New scale-up and design method for stirrer agitated batch mixing vessels

S.J. Khang, Octave Levenspiel · Chemical Engineering Science · 1976 · 130 citations

Engineering, Chemical Engineering, Industrial Engineering +16

Flooding of disc turbines in gas-liquid dispersions: A new description of the phenomenon

M.M.C.G. Warmoeskerken, J. M. Smith · Chemical Engineering Science · 1985 · 118 citations

Engineering, Chemical Engineering, Fluid Dynamics +13

Improved scale-up strategies of bioreactors

Lu‐Kwang Ju, George G. Chase · Bioprocess and Biosystems Engineering · 1992 · 110 citations

Engineering, Bioengineering, Biotechnology +12