Chemical Communications · 2015 · 53 citations · 12 references
PharmacyBioengineeringBiomedical EngineeringDrug DeliveryNanomaterialsNanotechnologyDrug EncapsulationInorganic NanoparticlesNanomaterials For Drug DeliveryNanomedicineNanoparticle Delivery SystemsNanoparticle SynthesisBiocompatible NanoparticlesGold Nanoparticle Drug DeliveryMetal NanoparticlesNanoparticlesSilica-based Nanoparticles
We introduce biodegradable hollow silica nanocapsules embedding arrays of 3 nm gold nanoparticles. The silica shell degrades in full serum in a few hours, potentially allowing the clearance of the capsules and their contents by the efficient renal pathway, and thereby overcoming accumulation issues typical of metal nanoparticles.
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