Successful Intermittent Prophylaxis With Trimethoprim/Sulfamethoxazole 2 Days per Week for <i>Pneumocystis carinii</i> (<i>jiroveci</i>) Pneumonia in Pediatric Oncology Patients

Abstract

Intermittent dosing of trimethoprim/sulfamethoxazole on 2 consecutive days per week is an effective alternative prophylactic regimen for P. carinii pneumonia in pediatric patients with leukemia and lymphoma. This analysis does not support a difference in neutropenia during maintenance therapy between patients who are treated with trimethoprim/sulfamethoxazole versus an alternative drug.