Intracortical lesions by 3T magnetic resonance imaging and correlation with cognitive impairment in multiple sclerosis

Abstract

Cortical lesions play an important role in CI. However, our results suggest that lesions that remain contained within the cortical ribbon do not play a more important role than ones extending into the adjacent white matter; furthermore, the size of the cortical lesion, and not the tissue-specific location, may better explain their correlation with CI.