The structure of demethoxyrapamycin

Abstract

The structure 2, 29-demethoxyrapamycin, is proposed for a new antibiotic from Streptomyceshygroscopicus and has been deduced by comparison of high field 1 H and 13 C nmr spectra, ir, uv, and mass spectra, and ORD/CD curves with those of the known antifungal antibiotic rapamycin 1.