Intravitreal Injection of Tissue Plasminogen Activator for Central Retinal Vein Occlusion.

Abstract

Intravitreal tPA can be injected safely and easily. Local injection of tPA should spare the patient the serious systemic risks of intravenous tPA administration, such as stroke. Given the morbidity of CRVO, further investigation with this therapy to establish both efficacy and safety seems warranted.