Publication | Closed Access
Palladium-Catalyzed Arylation and Heteroarylation of Indolizines
298
Citations
24
References
2004
Year
Cross-coupling ReactionEngineeringPalladium-catalyzed ArylationOrganic ChemistryOrganometallic CatalysisCatalysisEffective ProtocolChemistryPalladium-catalyzed Selective ArylationAsymmetric CatalysisSynthetic ChemistryEnantioselective SynthesisBiomolecular EngineeringElectrophilic Substitution Pathway
A highly effective protocol for palladium-catalyzed selective arylation and heteroarylation of indolizines at C-3 has been developed. Mechanistic studies unambiguously support an electrophilic substitution pathway for this transformation.
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